Search by keyword or browse our list of services.
Find a provider by specialty, location, or availability.
See current studies testing new drugs, devices, and equipment to find better ways to treat and help patients.
For life-threatening emergencies, call 911 without delay.
Search by specialty and location.
Receive the highest level of care from the region's leading providers.
Find a lab or imaging facility close to you.
Visit us to pay bills, ask billing questions, or request billing records.
Late-onset Tay-Sachs (LOTS) is a very rare genetic disease in which fatty compounds, called gangliosides, do not break down fully because the body produces too little of the enzyme hexosaminidase A (or hex A). Over time, gangliosides build up in the brain and damage brain nerve cells. This affects a person's mental functioning.
This condition is a recently discovered form of Tay-Sachs disease and occurs most often in people of Ashkenazi Jewish descent. People of French-Canadian or Cajun descent are also at a higher risk than the general population.
Symptoms of LOTS vary but usually include clumsiness or mood changes that begin between adolescence and the mid-30s. At first, symptoms are subtle and may go unnoticed. Other symptoms that may occur include:
Treatment for late-onset Tay-Sachs disease focuses on controlling symptoms. There is no cure. The life expectancy for a person with LOTS is unknown. Depending on the severity of the symptoms, the person may live as long as someone who does not have the disease.
To learn more, visit Healthwise.org
© 1995-2015 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
How do you define health? Physical? Mental? Social? Health goes beyond medical care. It's how we take care of ourselves, how we interact with our communities, how we take care of each other.
Let St. Luke's support your health, however you define it.